Qemu

qemu-system-x86_64 -usb -usbdevice disk:/dev/sdb
qemu-system-x86_64 -boot d -cdrom /dev/cdrom -m 512

create:
    $qemu-img create <filename>.img <size><M/G>
install:
    $qemu-system-x86_64 -m 4096 -cdrom <filename>.iso -hda <filename>.img -boot d
run:
    $qemu-system-x86_64 -m 4096 -drive file=<filename>.img,format=raw,index=0,media=disk